Glucagon-like Peptide 1 (GLP) is the new hope for type 2 diabetes

Diabetes is one of the most serious health problems of modern times. It is characterised by persistently high levels of blood glucose (sugar) in the body. At present, there is a whole range of effective medication for the treatment of Type 2 diabetes. Despite this, about 60 percent of populace diagnosed with Type 2 diabetes are not able to achieve good blood glucose control on their current treatment.

Recently discovered incretins (hormones that are secreted from enteroendocrine cells into the blood within minutes after eating) are Glucagon like peptide 1 (GLP1) which are impaired in Type 2 diabetes patients. Perhaps this may be a reason why patients with Type 2 diabetes are at increasing risk of abnormally high blood glucose levels.

Uncontrolled diabetes leads to increased risk of developing serious long-term complications like heart disease, stroke, erectile dysfunction, kidney failure, blindness, foot amputation and conditions related to poor blood circulation. Some of the medications can possibly lead to hypoglycaemia (too low blood sugar), weight gain and gastrointestinal intolerance. Type 2 diabetes can also coexist with other high-risk conditions such as high blood pressure, abnormal lipids (high cholesterol) and obesity.

GLP-1 is secreted in the intestine and it helps the pancreas produce more insulin in response to the presence of high blood sugar. People with Type 2 diabetes are generally affected by other metabolic disorders like being overweight, having higher blood pressure and lipid levels. The ability of GLP-1 to help in weight loss, beneficial effects on blood pressure and lipids and its ability to protect the beta-cells — the insulin-producing cells in our pancreas — makes it an effective tool to control diabetes.

Each individual’s diabetes is different and the appropriate treatment for each person can only be decided by his or her treating physician after a complete evaluation and taking into account various health parameters. Right medication plays a significant role in diabetes management. However, along with appropriate medicine, monitoring, healthy diet and regular exercise are necessary to control diabetes. Take smart decisions about what you eat, stay active, take your medications as advised by your doctor and you can enjoy a healthy and productive life.

In addition to this, GLP-1 works in multiple ways to keep Type 2 diabetes under control. It signals the pancreas to secrete more insulin when required, helps lower glucagon levels which stops the liver releasing unused sugar into the bloodstream, induces slower digestion to keep blood sugar levels from peaking in a short time interval after meals which translates into a reduced appetite and helps in preserving the number of insulin producing beta cells. (MR, Inputs: Agencies).

  • Ethel

    I was diagnosed with type 2 Diabetes and put on Metformin on June 26th,2016 I started the ADA diet and followed it 100% for a few weeks and could not get my blood sugar to go below 140, Finally i began to panic and called my doctor, he told me to get used to it, He said I would be on metformin my whole life and eventually insulin. At that point i knew something wasn’t right and began to do a lot of research. Then I found Lisa’s diabetes story (google ” How I helped myself from diabetes ” ) I read that article from end to end because everything the writer was saying made absolute sense. I started the diet that day and the next morning my blood sugar was down to 100 and now i have a fasting blood sugar between Mid 70’s and the 80’s. My doctor took me off the metformin after just three week of being on this lifestyle change,I have lost over 30 pounds and 6+ inches around my waist in a month. The truth is we can get off the drugs and help myself by trying natural methods!!

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